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當前位置:主頁 >> 標法輿情動態 >> 食品安全動態 >> 歐盟評估轉基因琉球曲霉菌株FL105SC生產的三酰甘油脂肪酶的安全性

歐盟評估轉基因琉球曲霉菌株FL105SC生產的三酰甘油脂肪酶的安全性

放大字體  縮小字體 發布日期:2023-10-19  來源:食品伙伴網  作者:澤夕
核心提示:2023年10月18日,歐盟食品安全局就一種食品酶三酰甘油脂肪酶(triacylglycerol lipase)的安全性評價發布意見。
   食品伙伴網訊  2023年10月18日,歐盟食品安全局就一種食品酶三酰甘油脂肪酶(triacylglycerol lipase)的安全性評價發布意見。
 
  據了解,這種食品酶是由轉基因琉球曲霉菌株FL105SC生產的,旨在以固定形式用于通過酯交換生產改性脂肪和油。
 
  經過評估,專家小組認為,在預期的使用條件下,不能排除通過飲食接觸引起過敏反應的風險,但這種情況發生的可能性很低。根據所提供的數據,小組得出結論,該食品酶在預期的使用條件下不會引起安全問題。部分原文報道如下:
 
  The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase; EC 3.1.1.3) is produced with the genetically modified Aspergillus luchuensis strain FL105SC by Advanced Enzyme Technologies Ltd. The genetic modifications do not give rise to safety concerns. The food enzyme is free from viable cells of the production organism and its DNA. It is intended to be used in an immobilised form for the production of modified fats and oils by interesterification. Genotoxicity tests did not indicate a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level (NOAEL) of 783 mg TOS/kg body weight per day. As the food enzyme is used in an immobilised form and as any residual amounts of the food enzyme–total organic solids (TOS) are removed during the food manufacturing process, dietary exposure was not calculated. A search for the similarity of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel considered that a risk of allergic reactions upon dietary exposure cannot be excluded, but the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
 
  本文由食品伙伴網食品資訊中心編輯,供網友參考,有任何疑問,請聯系news@foodmate.net。
 
 
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